Medical imaging — MRI denoising and gene expression from pathology

Speckle-noise reduction in MRI, and an MSc thesis on recovering gene-expression signal from digital pathology images.

The challenge

Speckle noise destroys diagnostic detail in MRI. Separately, gene-expression assays are slow and costly, while whole-slide pathology images are fast and cheap.

Architecture

Speckle-denoising models for MRI; and for pathology, graph neural networks, vision foundation models and adapted large-language-model techniques.

What I built

The thesis asks whether whole-slide pathology images can stand in for a gene-expression assay — recovering molecular-biology signal directly from gigapixel images, under a hard constraint on compute and latency.